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LMD (dextran 40) is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. It is administered by intravenous infusion. Also described as low viscous or low viscosity dextran, dextran 40 is prepared by acid hydrolysis and differential fractionation.
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Dextran is by far one of the most interesting non-toxic, bio-compatible macromolecules, an exopolysaccharide biosynthesized by lactic acid bacteria. It has been extensively used as a major component in many types of drug-delivery systems (DDS), which can be submitted to the next in-vivo testing stages, and may be proposed for clinical trials or pharmaceutical use approval. An important aspect.
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Call 800-438-1985 *. *Contact Medical Information. 8AM-9PM ET Monday to Friday; excluding holidays. dextran 40 () Description DESCRIPTION LMD (dextran 40) is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection.
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The esterification of dextran weakens inter- and intramolecular hydrogen bonding that damages the crystal structure and improves the flocculation performance of dextran in acidic environment [11].Etherification of dextran alters its physicochemical properties such as ionic strength, hydrophilic-lipophilic balance, and resistance against enzymatic degradation [12].
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Iron dextran side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Iron dextran can cause severe and sometimes fatal allergic reactions or severely low blood pressure. Call your doctor or seek medical help right away if you feel light-headed or if you suddenly have trouble breathing.
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Dextran, an exopolysaccharide formed by Leuconostoc mesenteroides (slimeproducing bacteria), and its derivatives are investigated for several therapeutic utilities. Dextranbased drug delivery system can become an innovative strategy in the treatment of several respiratory ailments as it offers numerous advantages, such as mucolytic action.
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Dextran is a polysaccharide made from natural sources of glucose by bacteria and with 1:6 glucoside links. [4] It can occur in various molecular weights, such as dextran 40 (40 kDa) and dextran 70 (70 kDa), which are both commonly utilized. [5] As a colloid, dextran osmotically expands plasma volume by restoring blood plasma lost through severe.
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Dextran will be a potential carrier for the delivery of antitumor drugs in the future, which provides the possibility of slow-release chemotherapy and targeted drug delivery. Herein, the preparation and drug delivery of dextran-drug complex were summarized and discussed in detail. Keywords: Dextran-drug complex, preparation, magnetic targeting.
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2.1 Dosage - Total dose infusion. The dose calculation for CosmoFer® is based on patient. s body weight according to the table below and is diluted in 500mLs of normal saline. If calculating the dose for an obstetric patient, use the pre-pregnancy weight. For obese patients use ideal body weight.
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Dextran is by far one of the most interesting non-toxic, bio-compatible macromolecules, an exopolysaccharide biosynthesized by lactic acid bacteria. It has been extensively used as a major component in many types of drug-delivery systems (DDS), which can be submitted to the next in-vivo testing stages, and may be proposed for clinical trials or.
Dextran and iron dextran injection uses, precautions & side effects
Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. It is administered by intravenous infusion. Dextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons.
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Iron-deficiency Anemia. Iron deficiency: Dose = 0.0442 (Desired Hgb - Observed Hgb) x Lean BW (kg) + (0.26 × Lean BW) LBW = Lean body weight in kg. A patient's lean body weight (or actual body weight if lessthan lean body weight) should be utilized when determining dosage. For males: LBW = 50 kg + 2.3 kg for each inch of patient's height.
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DESCRIPTION. INFeD (Iron Dextran Injection USP) is a dark brown, slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Each mL contains the equivalent of 50 mg of elemental iron (as an iron dextran complex), approximately 0.9% sodium chloride, in water for injection.
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Dextran is a nontoxic and biocompatible polysaccharide that has wide applications in pharmaceutical, biomedical, and industrial fields.. (DC-SIGN) family receptors: DC-SIGN (CD209) and L-SIGN (the liver and lymphatic endothelium homologue of DC-SIGN), the mannose receptor (CD206), and langerin. These receptors play a vital role in the uptake.
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Infed. Used for Anemia, Iron Deficiency. Infed (iron dextran) is used to raise the level of iron in the body for adults and children (age 4 months or older) who can't take iron supplements by mouth. It can be injected through the veins (IV) or into the muscle. Because Infed (iron dextran) can cause a very serious, and sometimes deadly, allergic.
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Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6". Dextran chains are of varying lengths (from 3 to 2000 kilodaltons).. The polymer main chain consists of α-1,6 glycosidic linkages between.